Expanding the Reactive Sulfur Metabolome: Intracellular and Efflux Measurements of Small Oxoacids of Sulfur (SOS) and H2S in Human Primary Vascular Cell Culture
Ottis Scrivner, Ahmed Ismaeel, Murugaeson R. Kumar, Kristina Sorokolet, Panagiotis Koutakis, Patrick J. Farmer
Molecules 2021, 26(23), 7160
Highlights
• H2S and SOS are produced and extruded in smooth muscle cells 20 x that in endothelial cells
• Hypoxia increased the generation of sulfenic acids while decreasing hydrogen sulfide